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NFKB p65 (Acetyl-Lys314/Lys315) Monoclonal Antibody, Biotin Conjugated

Product Specifications

Background

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

Synonyms

NF-kB p65 (Acetyl K314/K315) ; Acetyl-NF-kB p65 (K314/K315) ; NFkB-p65 (Acetyl K314/K315) ; RELA (Acetyl K314/K315) ; NF kB P65; NF-kB p65; NFKBp65; NF-_Bp65; p65 NF kappaB; p65 NFkB; NFKBp65; RELA; Transcription Factor p65; v rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B cells 3 (p65) ) ; V Rel Avian Reticuloendotheliosis Viral Oncogene Homolog A; v rel reticuloendotheliosis viral oncogene homolog A (avian) ; v-rel reticuloendotheliosis viral oncogene homolog A; p65NFKB; Avian reticuloendotheliosis viral (v rel) oncogene homolog A; MGC131774; NFKB 3; NFKB3; Nuclear Factor NF Kappa B p65 Subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 3; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B Cells.

Gene ID

5970

Swiss Prot

Q04206

Host

Mouse

Cross Reactivity

Human, Mouse, Rat

Target

NFKB p65 (Acetyl-Lys314/Lys315)

Clonality

Monoclonal

Isotype

IgG

Clone

4B11

Conjugation

Biotin

Source

KLH conjugated Synthesised phosphopeptide derived from human NFKBp65 around the acetylation site of Lys314/315

Applications

IHC-P, IHC-F

Purification

Purified by Protein G.

Concentration

1µg/µl

Dilution

IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

5970

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