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GSK-3 Beta Monoclonal Antibody

Product Specifications

Background

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]

Synonyms

Glycogen synthase kinase 3 beta; GSK 3 beta; GSK 3B; GSK3B; GSK3B protein; GSK3beta isoform; GSK3 beta; Glycogen synthase kinase-3 beta; GSK-3 beta; GSK3B_HUMAN.

Gene ID

P49841

Swiss Prot

2932

Cellular Locus

Cytoplasm, Nucleus, Cell membrane

Host

Mouse

Cross Reactivity

Human, Mouse, Rat

Immunogen

1-100/420

Target

GSK-3 Beta

Clonality

Monoclonal

Isotype

IgG

Clone

4C6

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human GSK-3 Beta

Applications

WB, IHC-P, IHC-F, IF

Purification

Purified by Protein G.

Concentration

1µg/µl

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

P49841

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