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RPS6KB1 Monoclonal Antibody

Product Specifications

Background

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013].

Synonyms

RPS6KB1; p70 (S6K) -alpha; ribosomal protein S6 kinase; p70 S6 Kinase; P70 Beta1; KS6B1_HUMAN; Ribosomal protein S6 kinase beta-1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6K-alpha; p70 S6KA; S6K; PS6K; S6K1; STK14A; p70-S6K; p70 S6KA; p70-alpha; S6K-beta-1; p70 (S6K) -alpha.

Gene ID

6198

Swiss Prot

P23443

Cellular Locus

Cytoplasm, Nucleus, Cell membrane

Host

Mouse

Cross Reactivity

Human, Rat

Target

RPS6KB1

Clonality

Monoclonal

Isotype

IgG

Clone

3D9

Conjugation

Unconjugated

Source

Recombinant human P70 S6 Kinase Protein

Applications

IHC-P, IHC-F, IF (ICC), IF

Purification

Purified by Protein G.

Concentration

1µg/µl

Dilution

IHC-P (1:200-400), IHC-F (1:100-500), IF (ICC) (1:50-200), IF ()

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

6198

Predicted Cross Reactivity

Mouse

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