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C-fos (8A3) Monoclonal Antibody, Biotin Conjugated

Product Specifications

Background

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq, Jul 2008].

Synonyms

Cellular oncogene fos; FBJ murine osteosarcoma viral v fos oncogene homolog antibody FBJ Osteosarcoma Virus; FOS; FOS protein; G0 G1 switch regulatory protein 7; G0S7; Oncogene FOS; Proto oncogene protein c fos; v fos FBJ murine osteosarcoma viral oncogene homolog; AP-1; p55; FOS_HUMAN; Proto-oncogene c-Fos; G0/G1 switch regulatory protein 7.

Gene ID

2353

Swiss Prot

P01100

Cellular Locus

Cytoplasm, Nucleus

Host

Mouse

Cross Reactivity

Human, Mouse, Rat

Target

C-fos

Clonality

Monoclonal

Isotype

IgG

Clone

8A3

Conjugation

Biotin

Source

Recombinant human c-fos Protein

Applications

WB, IHC-P

Purification

Purified by Protein G.

Concentration

1µg/µl

Dilution

WB (1:300-5000), IHC-P (1:200-400)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

2353

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