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Histone H3 (tri methyl K79) Monoclonal Antibody

Product Specifications

Background

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Synonyms

Histone Cluster 3, H3; H3 Histone Family, Member T; Histone 3, H3; H3FT; H3/G; H3/T; H3t; H3.4 ; Histone H3.1t ; HIST3H3; HGNC:4778; H31T_HUMAN

Gene ID

8290

Swiss Prot

Q16695

Cellular Locus

Nucleus

Host

Mouse

Cross Reactivity

Human, Mouse, Rat

Target

Histone H3 (tri methyl K79)

Clonality

Monoclonal

Isotype

IgG1

Clone

5A6

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human Histone H3 (tri methyl K79)

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (ICC)

Purification

Purified by Protein G.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

8290

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