CD68 Monoclonal Antibody
Product Specifications
Background
Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Synonyms
CD 68; CD68 antigen; CD68 molecule; DKFZp686M18236; GP110; Macrophage antigen CD68 (microsialin) ; macrosialin; SCARD1; Scavenger receptor class D member 1; macrosialin isoform A precursor; CD68_MOUSE; Macrosialin; Gp110; scavenger receptor class D, member 1; macrophage antigen CD68; LAMP4.
Gene ID
968
Swiss Prot
P34810
Cellular Locus
Cell membrane
Host
Mouse
Cross Reactivity
Human
Target
CD68
Clonality
Monoclonal
Isotype
IgG
Clone
8F3
Conjugation
Unconjugated
Source
Recombinant human CD68 1-100/354aa
Applications
IHC-P, IHC-F, IF
Purification
Purified by Protein G.
Concentration
1mg/ml
Dilution
IHC-P (1:200-400), IHC-F (1:100-500), IF ()
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
968
Predicted Cross Reactivity
Mouse, Rat
Curated Selection
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