PSA (Pa3) Monoclonal Antibody
Product Specifications
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
Synonyms
Prostate specic antigen; Gamma seminoprotein; hK3; Kallikrein 3; Kallikrein related peptidase 3; KLK 3; KLK2A1; KLK3; P 30 antigen; P30 antigen; Prostate Specic Antigen; PSA; Semenogelase; Seminin.
Gene ID
354
Host
Mouse
Cross Reactivity
Human
Target
PSA
Clonality
Monoclonal
Isotype
IgG
Clone
Pa3
Conjugation
Unconjugated
Source
Full length native protein purified from human
Applications
WB, ELISA, IHC-P, IF (IHC-P)
Purification
Purified by Protein G.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IF (IHC-P) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
354
Available Sizes
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