GLP-1 (1G9) Monoclonal Antibody
Product Specifications
Background
Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. GLP-1 is a potent stimulator of glucose-dependent insulin release. Play important roles on gastric motility and the suppression of plasma glucagon levels. May be involved in thesuppression of satiety and stimulation of glucose disposal in peripheral tissues, independent of the actions of insulin. Have growth-promoting activities on intestinal epithelium. May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, TSH, CRH, oxytocin, and vasopressin. Belongs to the glucagon family.
Synonyms
GCG; GLP 1; glucagon; Glucagon like peptide 1; GRPP; GLP-17-36; GLP-17-37; Oxyntomodulin; OXM; OXY; GLUC_HUMAN.
Host
Mouse
Cross Reactivity
Human, Mouse, Rat
Immunogen
1-31/31
Target
GLP
Clonality
Monoclonal
Isotype
IgG
Clone
1G9
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human GLP-1
Applications
WB, IHC-P, IF (IHC-P)
Purification
Purified by Protein G.
Concentration
1µg/µl
Dilution
WB (1:300-5000), IHC-P (1:200-400), IF (IHC-P) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Available Sizes
Curated Selection
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