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Human TLE1 Ready-To-Use IHC Kit

Product Specifications

Background

Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

Synonyms

C230057C06Rik; Estm14; Grg-1; GRG1; Tle4l; TLE 1; E (Sp1) homolog; Enhancer of split groucho 1; Enhancer of split groucho like protein 1; Enhancer of split groucho-like protein 1; ESG; ESG1; GRG1; TLE1; TLE1_HUMAN; Transducin like enhancer of split 1 (E (sp1) homolog Drosophila) ; Transducin like enhancer of split 1; Transducin like enhancer of split 1 homolog of Drosophila E (sp1) ; Transducin like enhancer protein 1; Transducin-like enhancer protein 1a

Cross Reactivity

Human

Target

Human TLE1

Sample Type

FFPE tissue

Components

PBS Buffer (powder) Antigen Retrieval Buffer Endogenous Peroxidase Blocking Buffer Blocking Buffer Primary Antibody Secondary Antibody Chromogen Component A Chromogen Component B Counter Staining Reagent Differentiation Reagent Mounting Media Control slide Datasheet

Storage Conditions

Storage and Stability: Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
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