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Human VDAC1 Ready-To-Use IHC Kit

Product Specifications

Background

Voltage-dependent anion channel (VDAC) proteins are abundant, pore-forming proteins belonging to the eukaryotic mitochondrial porins. It was discovered in the mitochondrial outer membrane. It also isexpressed in the plasma membrane. At least three different VDAC genes have been identified in vertebrates. VDAC proteins are known to play an essential role in cellular metabolism and in the early stages of apoptosis. For example, VDAC constitutes a major pathway by which metabolites such as ADP/ATP, succinate and citrate are exchanged between the cytosol and mitochondria. And VDAC1 in the plasmamembrane establishes a novel level of apoptosis regulation putatively via its redox activity.

Synonyms

Voltage dependent anion channel 1; AL033343; PORIN; VDAC; VDAC-1; VDAC1; Vdac5a

Cross Reactivity

Human

Target

Human VDAC1

Sample Type

FFPE tissue

Components

PBS Buffer (powder) Antigen Retrieval Buffer Endogenous Peroxidase Blocking Buffer Blocking Buffer Primary Antibody Secondary Antibody Chromogen Component A Chromogen Component B Counter Staining Reagent Differentiation Reagent Mounting Media Control slide Datasheet

Storage Conditions

Storage and Stability: Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.

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