Human Acetyl CoA carboxylase Ready-To-Use IHC Kit

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiplealternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.

A530025K05Rik; ACACAD; Gm738; I79_006999; ACAC; ACACA; ACACA_HUMAN; ACC alpha; ACC 1; ACC-alpha; ACC1; ACCA; Acetyl CoA carboxylase 1; Acetyl CoA carboxylase alpha; Acetyl Coenzyme A carboxylase alpha; Biotin carboxylase; COA1; HACC275 antibodya

PBS Buffer (powder) Antigen Retrieval Buffer Endogenous Peroxidase Blocking Buffer Blocking Buffer Primary Antibody Secondary Antibody Chromogen Component A Chromogen Component B Counter Staining Reagent Differentiation Reagent Mounting Media Control slide Datasheet

Storage and Stability: Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.