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Human ATP5A Ready-To-Use IHC Kit

Product Specifications

Background

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c) . This gene encodes the alpha subunit of the catalytic core. Alternatively spliced transcript variants encoding the different isoformshave been identified. Pseudogenes of this gene are located on chromosomes 9, 2, and 16.

Synonyms

AI035633; AL022851; AL023067; ATP5A; ATP5A1; ATP5A2; ATP5F1A; ATPM; COXPD22; D18Ertd206e; HEL-S-123m; MC5DN4; MOM2; ORM ATP synthase; H+ transporting; mitochondrial F1 complex; alpha subunit 1; ATP synthase; H+ transporting; mitochondrial F1 complex; alpha subunit; isoform1; cardiac muscle; ATP synthase; H+ transporting; mitochondrial F1 complex; alpha subunit; isoform2; non-cardiac muscle-like 2; ATP sythase (F1-ATPase) alpha subunit; ATP5AL2; ATP5AMOM2; ATPMATP synthase subunit alpha; mitochondrial; cardiac muscle; EC 3.6.3; EC 3.6.3.14; hATP1; mitochondrial ATP synthetase; oligomycin-resistant; OMR; ORMATP synthase alpha chain; mitochondrial.

Cross Reactivity

Human

Target

Human ATP5A

Sample Type

FFPE tissue

Components

PBS Buffer (powder) Antigen Retrieval Buffer Endogenous Peroxidase Blocking Buffer Blocking Buffer Primary Antibody Secondary Antibody Chromogen Component A Chromogen Component B Counter Staining Reagent Differentiation Reagent Mounting Media Control slide Datasheet

Storage Conditions

Storage and Stability: Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.

Frequently Asked Questions

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