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Human HES5 Ready-To-Use IHC Kit

Product Specifications

Background

Hairy and Enhancer-of-split homologues 5 (HES5) is a helix-loop-helix transcriptional factor that negatively regulates cell differentiation during embryogenesis. It contains one basic helix-loop-helix (bHLH) domain and one Orange domain. HES5 is reported to be a down stream effector of the Notch Signaling Pathway and is expressed in advanced ovarian serous adenocarcinomas as well as in cervical squamous carcinoma. Reports also suggest that HES5 is abundantly expressed in osteoarthritis along with Notch1 and Jagged1.

Synonyms

BHLHB38, Hes-5, HES5, Hairy and enhancer of split 5, HES 5, HES5 protein, MGI:104876.

Cross Reactivity

Human

Target

Human HES5

Sample Type

FFPE tissue

Components

PBS Buffer (powder) Antigen Retrieval Buffer Endogenous Peroxidase Blocking Buffer Blocking Buffer Primary Antibody Secondary Antibody Chromogen Component A Chromogen Component B Counter Staining Reagent Differentiation Reagent Mounting Media Control slide Datasheet

Storage Conditions

Storage and Stability: Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.

Frequently Asked Questions

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