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Human CK10/Cytokeratin 10 Ready-To-Use IHC Kit

Product Specifications

Background

Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (i.e., skin) and non-keratinizing cells (i.e. mesothelial cells) . Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8. 5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides) . At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification.

Synonyms

CK10, Ka10, KER10, KPP, KRT10, 56 kDa cytokeratin, BCIE, BIE, CK 10, CK-10, ck10, Cytokeratin 10, Cytokeratin 6B, Cytokeratin VIB, Cytokeratin-10, Cytokeratin10, EHK, k10, K1C10_HUMAN, Keratin 10, Keratin, Keratin type i cytoskeletal 10, Keratin type I cytoskeletal 59 kDa, Keratin-10, Keratin10, kpp, Krt 1 10, Krt 10, krt10 , type I cytoskeletal 10, Type I keratin Ka10, Keratin, type I cytoskeletal 10, Cytokeratin-10, K10.

Cross Reactivity

Human

Target

Human CK10/Cytokeratin 10

Sample Type

FFPE tissue

Components

PBS Buffer (powder) Antigen Retrieval Buffer Endogenous Peroxidase Blocking Buffer Blocking Buffer Primary Antibody Secondary Antibody Chromogen Component A Chromogen Component B Counter Staining Reagent Differentiation Reagent Mounting Media Control slide Datasheet

Storage Conditions

Storage and Stability: Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.

Frequently Asked Questions

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