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Mouse EAAT2 Ready-To-Use IHC Kit

Product Specifications

Background

Excitatory amino acid transporter 2 (EAAT2) is a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis (ALS.) Alternatively spliced transcript variants of this gene have been identified.

Synonyms

1700091C19Rik; 2900019G14Rik; AI159670; EAAT2; Glt; GLT-1; GLT1; HBGT; MGLT1; SLC1A2; EIEE41; Sodium-dependent glutamate/aspartate transporter 2; Solute carrier family 1 member 2.

Cross Reactivity

Mouse

Target

Mouse EAAT2

Sample Type

FFPE tissue

Components

PBS Buffer (powder) Antigen Retrieval Buffer Endogenous Peroxidase Blocking Buffer Blocking Buffer Primary Antibody (Mouse EAAT2 Rabbit pAb) Secondary Antibody (Goat Anti-Rabbit IgG H&L / HRP) Chromogen Component A Chromogen Component B Counter Staining Reagent Differentiation Reagent Mounting Media Control slide (Mouse cerebellum) Datasheet

Storage Conditions

Storage and Stability: Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.

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