Human Nestin Ready-To-Use IHC Kit

Nestin is a Class VI intermediate filament abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells. Nestin has been widely used as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells. Also, Nestin is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumors. Highly specific antibodies to human Nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells. Nestin expression has been observed in pancreatic hematopoietic stem cell populations, and is considered a novel angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue.

PBS Buffer (powder) Antigen Retrieval Buffer Endogenous Peroxidase Blocking Buffer Blocking Buffer Primary Antibody (Human Nestin Mouse mAb) Secondary Antibody (AffiniPure Goat Anti-Mouse IgG H&L) Chromogen Component A Chromogen Component B Counter Staining Reagent Differentiation Reagent Mounting Media Control slide (Human brain) Datasheet

Storage and Stability: Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.