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CD79a Antibody (PE)

Mouse monoclonal antibody conjugated to PE which recognizes CD79a that expressed in B-cells. Defects in CD79A are the cause of agammaglobulinemia type 3 (AGM3) . The cytoplasmic tails of CD79A contains an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine

Product Specifications

Product Name Alternative

BCR alpha, Ig-alpha, MB-1, IGA

UniProt

P11912

Reactivity

Bovine, Canine, Equine, Gallus, Guinea pig, Human, Mouse, Porcine, Primate, Rabbit, Rat

Immunogen

Synthetic peptide corresponding to C terminal amino acids 208-222 of human CD79a

Target

CD79a

Clonality

Monoclonal

Clone

HM47

Conjugation

PE

Field of Research

Immunology & Inflammation

Purification

Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Notes

For research use only.

Applications Notes

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Intracellular staining.

Tested Applications

FC

Preservative

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Isotype

Mouse IgG1 kappa

Entrez

973

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