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CD123 Antibody (PE)

Mouse monoclonal antibody conjugated to PE which recognizes CD123 that is also known as IL-3 receptor subunit alpha, IL-3R-alpha and IL3RA, is a single-pass type I membrane protein which is a member of the type I cytokine receptor family and Type 5 subfamily. CD123 is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias. CD123 is also a useful new marker for distinguishing B-cell disorders with circulating villous lymphocytes.

Product Specifications

Product Name Alternative

IL3RA, MGC34174, hIL-3Ra

UniProt

P26951

Reactivity

Human

Immunogen

IL3 receptor alpha chain expressed on the surface of transiently transfected COS cells

Target

CD123

Clonality

Monoclonal

Clone

6H6

Conjugation

PE

Field of Research

Immunology & Inflammation

Purification

Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Notes

For research use only.

Applications Notes

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Tested Applications

FC

Preservative

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Isotype

Mouse IgG1

Entrez

3563

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