(+) -Glaucarubinone
(+) -Glaucarubinone is a quassinoid compound and a potent activator protein-1 (AP-1) inhibitor with an EC50 value of 0.13 µM. (+) -Glaucarubinone has anti-tumor activity and can be used in the research of tumors such as hepatocellular carcinoma[1][2][3].
Product Specifications
CAS Number
1259-86-5
UNSPSC
12352005
Target
AP-1; Cadherin; MMP; p38 MAPK; PERK
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton; Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/plus-glaucarubinone.html
Purity
96.46
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@]3([H])[C@]45[C@@]([C@H]([C@H]([C@@]3(OC5)O)O)C)([H])[C@H](C(O[C@]4([H])C[C@@]1([H])C(C)=CC([C@H]2O)=O)=O)OC([C@@](C)(O)CC)=O
Molecular Formula
C25H34O10
Molecular Weight
494.53
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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