CZL55
CZL55 is a caspase-1 inhibitor with an IC50 value of 24 nM. CZL55 can be used for the research of febrile seizures (FS) [1].
Product Specifications
CAS Number
[667408-87-9]
UNSPSC
12352005
Target
Caspase
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/czl55.html
Purity
98.92
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(O)CCCC(NC1=CC=CC(C(NC2=CC=C(OC)C=C2OC)=O)=C1)=O
Molecular Formula
C20H22N2O6
Molecular Weight
386.40
References & Citations
[1]Tang Y, et al. Structure-based discovery of CZL80, a caspase-1 inhibitor with therapeutic potential for febrile seizures and later enhanced epileptogenic susceptibility. Br J Pharmacol. 2020 Aug;177 (15) :3519-3534.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Caspase 1
Available Sizes
Curated Selection
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