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HLA-DR Antibody (FITC)

Mouse monoclonal antibody conjugated to FITC which recognizes HLA-DR that belongs to the MHC class II family. It localized in endoplasmic reticulum membrane, golgi apparatus. It binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) . HLA-DR is a heterodimeric transmembrane protein composed of alpha and beta subunits and plays an important role in the presentation of peptides to CD4+ T lymphocytes.

Product Specifications

Reactivity

Canine, Human, Primate

Immunogen

Human B lymphocytes

Target

HLA-DR

Clonality

Monoclonal

Clone

L243

Conjugation

FITC

Field of Research

Immunology & Inflammation

Purification

Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Notes

For research use only.

Applications Notes

Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

Tested Applications

FC

Preservative

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Isotype

Mouse IgG2a kappa

Entrez

35

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