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CD105 Antibody (Biotin)

Mouse monoclonal antibody conjugated to Biotin which recognizes CD105 that also known as Endoglin, is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) . It is a major glycoprotein of vascular endothelium. It may play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.

Product Specifications

Product Name Alternative

Endoglin, END, ENG, HHT1, ORW1

UniProt

P17813

Reactivity

Human, Porcine

Immunogen

Recombinant Vaccinia virus containing the human CD105 (L-isoform) cDNA.

Target

CD105

Clonality

Monoclonal

Clone

MEM-229

Conjugation

Biotin

Field of Research

Cardiovascular Research; Immunology & Inflammation

Purification

Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.

Concentration

1 mg/ml

Storage Conditions

Store at 2-8°C. Do not freeze.

Notes

For research use only.

Applications Notes

Flow cytometry: Recommended dilution: 8 μg/ml; positive control: Kg1 human acute myelogenous leukemia cell line.

Tested Applications

FC, ICC, IHC-Fr, WB

Preservative

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Isotype

Mouse IgG2a

Entrez

2022

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