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CD63 Antibody (Biotin)

Mouse monoclonal antibody conjugated to Biotin which recognizes is a CD63 that is lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is observed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. CD63 is belongs to the TM4 superfamily of leukocyte glycoproteins. CD63 may participates in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome.

Product Specifications

Product Name Alternative

OMA81H, Granulophysin, Tetraspanin-30, Tspan-30, MLA1, ME491, LAMP-3, OMA81H, TSPAN30

UniProt

P08962

Reactivity

Human

Immunogen

HPB-ALL T cell line

Target

CD63

Clonality

Monoclonal

Clone

MEM-259

Conjugation

Biotin

Field of Research

Immunology & Inflammation

Purification

Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.

Concentration

1 mg/ml

Storage Conditions

Store at 2-8°C. Do not freeze.

Notes

For research use only.

Applications Notes

Flow cytometry: Recommended dilution: 1-3 μg/ml; positive material: activated platelets, neutrophils and basophils.

Tested Applications

FC, ICC, IHC-P, IP

Preservative

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Isotype

Mouse IgG1

Entrez

967

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