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Notch1 Antibody (APC)

Mouse monoclonal antibody conjugated to APC which recognizes Notch 1 that belongs to the NOTCH family transmembrane receptors that play important roles in development and the determination of cell fate. It expressed in fetal tissues most abundant in spleen, brain stem and lung. Notch 1 has functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination.

Product Specifications

Product Name Alternative

AOS5, TAN1, hN1, AOVD1

UniProt

P46531

Reactivity

Human, Mouse

Immunogen

GST fusion protein containing cdc10-NCR region of mouse Notch1

Target

Notch1

Clonality

Monoclonal

Clone

MN1A

Conjugation

APC

Field of Research

Cardiovascular Research

Purification

Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Concentration

0.1 mg/ml

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Notes

For research use only.

Applications Notes

Flow cytometry: Recommended dilution: 1-5 μg/ml. Intracellular staining.

Tested Applications

FC

Preservative

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Isotype

Mouse IgG1 kappa

Entrez

4851

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