CD163 Antibody (APC)

Mouse monoclonal antibody conjugated to APC which recognizes CD163 that also designated M130 is a macrophage-associated antigen that is a member of the scavenger receptor cysteine-rich superfamily. CD163 is a receptor that scavenges hemoglobin by mediating endocytosis of haptoglobin- hemoglobin complexes. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme.

Product Specifications

Product Name Alternative

MM130, SCARI1

UniProt

Q86VB7

Reactivity

Human

Immunogen

Hairy cell leukemia cells

Target

CD163

Clonality

Monoclonal

Clone

GHI/61

Conjugation

APC

Field of Research

Immunology & Inflammation

Purification

Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Notes

For research use only.

Applications Notes

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.