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CD180 Antibody (APC)

Mouse monoclonal antibody conjugated to APC which recognizes CD180 that belongs to the toll-like receptor family. It is expressed on mature B cells, monocytes/macrophages and dendritic cells. CD180 is a signal transduction molecule and plays a role in regulation of B cell growth and death and also play a role in the innate immune response to bacterial lipopolysaccharide, through co-operation with MD-1 and TLR4.

Product Specifications

Product Name Alternative

LY64, Ly78, RP105, Bgp95

UniProt

Q99467

Reactivity

Human

Immunogen

Human tonsillar B cells

Target

CD180

Clonality

Monoclonal

Clone

G28-8

Conjugation

APC

Field of Research

Immunology & Inflammation

Purification

Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Notes

For research use only.

Applications Notes

Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Tested Applications

FC

Preservative

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Isotype

Mouse IgG1 kappa

Entrez

4064

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