What is the catalog number for MZ1?

The catalog number for MZ1 is bs-83830C.

What sizes are available for MZ1?

MZ1 is available in the following size(s): 1 mg, 5 mg.

How many pack sizes does MZ1 come in?

MZ1 is available in 2 different pack sizes.

MZ1 is currently made to order / not held in immediate stock. Contact us for lead time.

MZ1

Product Specifications

Background

MZ1 consists of JQ1 tethered to a ligand for the E3 ubiquitin ligase VHL and is a selective degrader of the BET bromodomain protein BRD4. It rapidly and potently induces reversible, long-lasting and unexpectedly selective degradation of BRD4 over BRD2 and BRD3.1 It exerts anticancer effects in acute myeloid leukemia by targeting c-Myc and ANP32B.2 An important tool for studying the effects of BRD4 degradation in cancer therapy.3