MZ1
Product Specifications
Background
MZ1 consists of JQ1 tethered to a ligand for the E3 ubiquitin ligase VHL and is a selective degrader of the BET bromodomain protein BRD4. It rapidly and potently induces reversible, long-lasting and unexpectedly selective degradation of BRD4 over BRD2 and BRD3.1 It exerts anticancer effects in acute myeloid leukemia by targeting c-Myc and ANP32B.2 An important tool for studying the effects of BRD4 degradation in cancer therapy.3
Conjugation
Unconjugated
Buffer
Pale-yellow solid
Storage Conditions
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV672146 1.0 µg DNA
GYG1 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)
Sign In for Pricing
View Details 
MBS7148287 Inquire
Rabbit anti-Shigella flexneri gadB Polyclonal Antibody
Sign In for Pricing
View Details PB9910-PE 100 µg/Vial
Anti-ZBTB7A Antibody Picoband® (PE Conjugate)
Sign In for Pricing
View Details 
abx171192 1 mL
Aminoacyl tRNA Synthetase Complex Interacting Multifunctional Protein 1 (AIMP1) Antibody
Sign In for Pricing
View Details ![7-O- (Triethylsilyl) -2’-O-tert-butyl (dimethyl) silyl-4-desacetyl-2-debenzoyl-[2,4]oxol Paclitaxel](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
022210 5 mg
7-O- (Triethylsilyl) -2’-O-tert-butyl (dimethyl) silyl-4-desacetyl-2-debenzoyl-[2,4]oxol Paclitaxel
Sign In for Pricing
View Details