Alpelisib
Product Specifications
Background
Alpelisib is a potent and selective (IC50s = 7.4 nM PI3Kα; 2.2 µM PI3Kß; 1.2 µM PI3KIδ; 50-fold selectivity against 442 tested kinases) PI3Kα inhibitor.1 Approved for use in the treatment of HR (+), HER2 (-), PIK3CA-mutated breast cancer. Alpelisib has been used in combination with various chemotherapeutics to treat ovarian2, colorectal3, kidney4, bladder5, and head and neck6 cancers.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C
Available Sizes
Curated Selection
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