TPCA-1
Product Specifications
Background
Selective inhibitor of IκB kinase 2 (IKK2) (IC50 = 17.9 nM) .1 Inhibits production of pro-inflammatory cytokines in arthritis and other animal models of inflammation.1,2 Also attenuates NLRP3 inflammasome activation in THP-1 myeloid cells, and suppresses IL1β-induced proliferation, migration, and invasion of HeLa cells.3,4 Continuous exposure to TPCA-1 promotes expansion of hematopoietic stem/progenitor cells (HSPCs) via improved glycolysis and limited ROS production.5
Conjugation
Unconjugated
Buffer
Pale yellow solid
Storage Conditions
-20°C
Product Datasheet
https://www.biossantibodies.com/datasheets/bs-83442C
Available Sizes
Curated Selection
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