What is the catalog number for UH15-38·2HCl?

The catalog number for UH15-38·2HCl is bs-83419C.

What sizes are available for UH15-38·2HCl?

UH15-38·2HCl is available in the following size(s): 5 mg, 25 mg.

How many pack sizes does UH15-38·2HCl come in?

UH15-38·2HCl is available in 2 different pack sizes.

Is UH15-38·2HCl in stock?

UH15-38·2HCl is currently made to order / not held in immediate stock. Contact us for lead time.

UH15-38·2HCl

Product Specifications

Background

UH15-38 is a potent (IC50 = 20 nM) inhibitor of RIPK3 with excellent cellular activity. It blocked TNF-induced necroptosis in primary mouse embryonic fibroblasts (IC50 = 98 nM) . UH15-38 selectively blocked influenza A-induced necroptosis over apoptosis in mouse alveolar epithelial cells, mouse embryonic fibroblasts, and human M29 cells at nanomolar levels. It attenuated influenza A-induced lung injury and lethality in vivo.