XL413·HCl
Product Specifications
Background
XL413 is a potent (IC50 = 4.8 nM) ATP-competitive inhibitor of the important DNA replication initiation kinase Cdc7 (DDK) .1 It increases the efficiency of homology directed DNA repair in CRISPR-Cas9 gene editing.2 XL413 acted synergistically with other chemotherapy agents in various cancer models.3-5
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C
Available Sizes
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