What is the catalog number for RO-3306?

The catalog number for RO-3306 is bs-83377C.

What sizes are available for RO-3306?

RO-3306 is available in the following size(s): 5 mg, 25 mg.

How many pack sizes does RO-3306 come in?

RO-3306 is available in 2 different pack sizes.

RO-3306 is currently made to order / not held in immediate stock. Contact us for lead time.

RO-3306

Product Specifications

Background

RO-3306 is a selective inhibitor of CDK1 (IC50 = 35 nM versus CDK2 IC50 = 340nM) .1,2 It induces G2/M phase cell cycle arrest and apoptosis. Inhibition of CDK1 with RO-3306 has been shown to have synergistic effects with PARP inhibitors in treating various breast cancers.3,4 It has also been demonstrated to overcome apoptotic resistance in BRAFV600E human colorectal cancer cells.5