Concanamycin A

A potent and specific inhibitor of the vacuolar (V-type) H+-ATPase which can induce apoptotic cell death in various cell lines.1,2 Inhibits cell surface expression of virus envelope glycoproteins.3 Dramatically increases the rate of extracellular vesicle release from a variety of cell types.4 Inhibits autophagy by blocking lysosomal acidification.5