What is the catalog number for Purvalanol A?

The catalog number for Purvalanol A is bs-83340C.

What sizes are available for Purvalanol A?

Purvalanol A is available in the following size(s): 5 mg, 25 mg.

How many pack sizes does Purvalanol A come in?

Purvalanol A is available in 2 different pack sizes.

Is Purvalanol A in stock?

Purvalanol A is currently made to order / not held in immediate stock. Contact us for lead time.

Purvalanol A

Product Specifications

Background

Cyclin-dependent kinase inhibitor. IC50s= 4, 70, 35, 75 and 850 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk5/p35 and cdk4/cyclin D1 and respectively.1 Reversibly arrests synchronized cells in G1 and G2 phase.2 Induces ER stress-mediated apoptosis and autophagy in colon cancer cells.3 Suppresses Src-mediated transformation by inhibiting both CDKs and c-Src.4 In cells transformed with MYC, purvalanol A rapidly down-regulates survivin expression and induces MYC-dependent apoptosis.5 Cell permeable.