Apicidin
Product Specifications
Background
Apicidin is a fungal toxin that is a potent, cell permeable inhibitor of histone deacetylases (HDAC’s) .1 It also displays antitumor properties by inducing changes in p21WAF1/Cip1 and gelsolin gene expression causing cell cycle arrest in the G1 phase.2 Apicidin dramatically decreases HIF-1α protein levels and transcriptional activity in human and mouse tumor cell lines.3
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C
Available Sizes
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