NSC47924
Product Specifications
Background
A potent inhibitor of the Leucine-rich repeat protein phosphatase (PHLPP) an enzyme which is a negative regulator of Akt and PKC (IC50=4 M) .1 Increases AKT signaling in cells and prevents apoptosis. Also inhibits the 67 kDa laminin receptor (LR) interaction with laminin (LM) and selectively blocks LR-293 cell adhesion to LM IC50=19.35 M) impairing cell migration and invasion.2 Affects 37/67 kDa LR cell surface localization and interaction with cellular prion protein.3
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K0296508 1.0 µg DNA
C14orf17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)
Sign In for Pricing
View Details 
GTR15361032 1 Vial
Lentiviral human CCDC62 sgRNA gene knockout kit - Lentiviral human CCDC62 sgRNA gene knockout kit (25)
Sign In for Pricing
View Details