Cantharidin
Product Specifications
Background
Inhibits protein phosphatase 2A (Ki=0.19 μM) and PP1 (Ki=1.1 μM) 1. Displays >500-fold selectivity over PP2B. Suppresses growth and migration of PANC-1 pancreatic cancer cells via phosphorylation and degradation of β-catenin2. Arrests G2/M transition via JNK/Sp1-dependent down-regulation of CDK13. Cell permeable. Warning: Avoid skin contact, may cause skin irritation or blistering.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C
Available Sizes
Curated Selection
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