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Z-Leu-Arg-AMC

Product Specifications

Background

Z-Leu-Arg-AMC (156192-32-4) is a sensitive Cathepsin K fluorogenic substrate (Km=8µM, kcat/Km=4 x 105 M-1s-1) 1-3. It is cleaved more slowly by the following cathepsins (kcat/Km: B (105) 4, F (106) 4, L (106) 4,5, L2/V (104) 5, S (105) 2,4,5. Also cleaved by malaria parasite proteases berghepain6, vivapain-2 and -37, and falcipain-1, -2, and -36,8,9. Excitation: 365nm, Emission: 440nm.

Conjugation

Unconjugated

Buffer

White solid

Storage Conditions

-20°C (protect from light)

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