What is the catalog number for HET0016?

The catalog number for HET0016 is bs-83104C.

What sizes are available for HET0016?

HET0016 is available in the following size(s): 5 mg, 25 mg.

How many pack sizes does HET0016 come in?

HET0016 is available in 2 different pack sizes.

HET0016 is currently made to order / not held in immediate stock. Contact us for lead time.

HET0016

Product Specifications

Background

HET0016 (339068-25-6) inhibits 20-hydroxyeicosatetraenoic acid (20-HETE) biosynthesis via omega oxidation of arachidonic acid mediated by CYP4A and 4F (IC50=8.9 nM in human renal microsomes) .1 It displays neuroprotective effects in a rat model of traumatic brain injury via inhibition of neuronal pyroptosis.2 HET0016 attenuates cerebral ischemia-reperfusion injury3 as well as oxidative injury and peripheral nerve damage in type-2 diabetic mice4. It alleviates myocardial oxidative stress5 and restores endothelial function suggesting therapeutic potential in obesity-associated vascular disease6.