What is the catalog number for C-DIM 8?

The catalog number for C-DIM 8 is bs-83099C.

What sizes are available for C-DIM 8?

C-DIM 8 is available in the following size(s): 5 mg, 25 mg.

How many pack sizes does C-DIM 8 come in?

C-DIM 8 is available in 2 different pack sizes.

C-DIM 8 is currently made to order / not held in immediate stock. Contact us for lead time.

C-DIM 8

Product Specifications

Background

C-DIM 8 is an antagonist of the orphan nuclear receptor Nur77 (NR4A1, TR3) .1 Induces reactive oxygen species and ER stress in pancreatic cancer cells.2 C-DIM 8 mimics the effect of Nur77 knockdown in non-small-cell lung cancer A549 and H460 cells, inhibiting cell growth and inducing apoptosis which was accompanied by decreased expression of survivin and inhibition of mTORC1 signaling.3 Inhibits the expression of β1- and β3-integrin and blocks integrin-dependent breast cancer cell migration.4 Decreases expression of the histone methyltransferase G9A (EHMT2) in a variety of cancer cell lines.5