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HLA-DR Antibody

Mouse monoclonal antibody to HLA-DR which belongs to the MHC class II family. It localized in endoplasmic reticulum membrane, golgi apparatus. It binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) . HLA-DR is a heterodimeric transmembrane protein composed of alpha and beta subunits and plays an important role in the presentation of peptides to CD4+ T lymphocytes.

Product Specifications

Reactivity

Canine, Human, Primate

Immunogen

Human B lymphocytes

Target

HLA-DR

Clonality

Monoclonal

Clone

L243

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Purification

Purified by protein-A affinity chromatography.

Concentration

1 mg/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Functional application: Blocking. Flow cytometry: Recommended dilution: 1-4 μg/ml

Tested Applications

FA, FC, ICC, IHC-Fr, IHC-P, IP, WB

Preservative

Phosphate buffered saline (PBS), pH 7.4

Isotype

Mouse IgG2a kappa

Entrez

35

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