SSAA09E1
Product Specifications
Background
SSAA09E1 (433212-75-0) is an inhibitor of SARS coronavirus (SARS-CoV) replication by blocking viral entry (EC50=6.7mM) . SSAA09E1 was discovered by screening a chemical library for blocking of entry of HIV-1 pseudotyped with SARS-CoV surface glycoprotein S. The compound acts via inhibition of cathepsin L (IC50=5.33 mM), a host protease required for processing of SARS-S during viral entry. Cathepsin B is not inhibited.1 The compound was also shown to inhibit tyrosinase (IC50=0.14 mM) .2
Conjugation
Unconjugated
Buffer
Beige solid
Storage Conditions
-20°C
Available Sizes
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