What is the catalog number for GSK872?

The catalog number for GSK872 is bs-83050C.

What sizes are available for GSK872?

GSK872 is available in the following size(s): 5 mg, 25 mg.

How many pack sizes does GSK872 come in?

GSK872 is available in 2 different pack sizes.

GSK872 is currently made to order / not held in immediate stock. Contact us for lead time.

GSK872

Product Specifications

Background

GSK872 is a potent (IC50 = 1.8nM domain binding; IC50 = 1.3 nM kinase activity) and selective inhibitor of receptor interacting protein 3 (RIP3) .1 It is able to prevent necroptosis, virus-induced necrosis, and TLR3-induced necrosis.1,2 GSK872 can induce Caspase8-mediated apoptosis at higher concentrations (e.g.3 µM) .2