Quizartinib
Product Specifications
Background
Quizartinib is a potent and selective inhibitor of FLT3 (Kd = 1.6nM, IC50 = 0.56 nM MV4-11 cells) .1 It is in clinical trials for treatment of Acute Myelogenous Leukemia (AML) .2,3 Quizartinib priming resulted in prevention of myelosuppression in mice treated with 5-FU and Gemcitabine.4 Quizartinib showed significant reversal of ABCG2-mediated multidrug resistance (@ 3 µM) via antagonism of drug efflux function.5,6
Conjugation
Unconjugated
Buffer
Off-white to beige solid
Storage Conditions
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K3738805 3x 1.0 µg
Dmrtc2 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
Sign In for Pricing
View Details ![[1- (2,2-Difluoro-2-phenylethyl) -1H-1,2,3-triazol-4-yl]methanol](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
ZVC48257-01 50 mg
[1- (2,2-Difluoro-2-phenylethyl) -1H-1,2,3-triazol-4-yl]methanol
Sign In for Pricing
View Details ZVC48257-02 0.5 g
[1- (2,2-Difluoro-2-phenylethyl) -1H-1,2,3-triazol-4-yl]methanol
Sign In for Pricing
View Details 
GTR10359943 96 Well
Bovine Cytochrome c oxidase subunit 4 isoform 2, mitochondrial (COX4I2) ELISA Kit
Sign In for Pricing
View Details