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Binimetinib

Product Specifications

Background

Binimetinib (606143-89-9) is a potent (IC50 = 12 nM) and selective allosteric inhibitor of MEK1/2.1,2 Recently approved by the FDA for treatment of melanoma in combination with Encorafenib. Binimetinib has had limited success as monotherapy but has shown promise in combination with other chemotherapeutic agents.3-5

Conjugation

Unconjugated

Buffer

White solid

Storage Conditions

-20°C

Available Sizes

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