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JNK-IN-8

Product Specifications

Background

JNK-IN-8 is a potent and selective irreversible JNK inhibitor (IC50s=4.67, 18.7 and 0.98 nM for JNK1, 2 and 3 respectively) .1 JNK blockade with JNK-IN-8 overcomes PD-L1-mediated resistance to chemotherapy in colorectal cancer.2 Improves ARDS-induced cognitive impairment by inhibition of JNK/NF-kB-mediated NLRP3 inflammasome activation.3

Conjugation

Unconjugated

Buffer

Pale yellow solid

Storage Conditions

-20°C

Available Sizes

Frequently Asked Questions

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