BO-264
Product Specifications
Background
BO-264 is a potent (IC50 = 188 nM) inhibitor of transforming acidic coiled-coil 3 (TACC3), an important protein involved in microtubule stability and centrosome integrity.1 TACC3 is frequently upregulated in a broad range of cancers. BO-264 displayed significant anticancer activity in greater than 90% of cell lines in the NCI-60 human cancer cell line panel. Active in vivo in mice injected with JIMT-1 and EMT6 breast cancer cells as well as mouse colon cancer xenografts HCT-116 and CT-26.
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
VAng-0361Lsx-50gEcoli 50 µg (E. coli)
Recombinant Shigella Sonnei yejK Protein (aa 1-335)
Sign In for Pricing
View Details 
UNC50-4920R 50 µg
Recombinant Rhesus Macaque UNC50 Protein, His (Fc)-Avi-tagged
Sign In for Pricing
View Details 
