R428
Product Specifications
Background
R428 (1037624-75-1) is a potent and selective inhibitor of AXL kinase (IC50 = 1.4nM) .1 R428 has been shown to overcome chemotherapy resistance to various agents in multiple cancer models.2-5 AXL has been shown to suppress myeloid cell activation and function – combined AXL inhibition with R428 and PD-1 blockade showed potent synergistic antitumor effects.6,7
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb2571433 200 µL
Zebrafish Col6a2 Rabbit Polyclonal Antibody (Cy3)
Sign In for Pricing
View Details 
GTR15093828 1 Vial
Lentiviral human CHCHD3 shRNA (UAS) - Lentiviral human CHCHD3 shRNA (UAS, RFP) (100)
Sign In for Pricing
View Details A03699-2-carrier-free 100 µg/Vial
Anti-GSTA4 Antibody Picoband®, Carrier-free
Sign In for Pricing
View Details 662892 12 pieces per CAR
SensoPlates plate, 24w, glass bottom, 0,5-1,5ml/w, polystyrene, black, lid with condensation rings, subpacked per piece, STERILE, 12 pieces per CAR
Sign In for Pricing
View Details 
IRBAHUMYCEAC13C100UL 100 µL
Rabbit Anti Human MYC Monoclonal Clone EAC-13 100UL
Sign In for Pricing
View Details