ABX-1431
Product Specifications
Background
Potent (IC50 = 14 nM in vitro, 2.2 nM in human PC3 cells) and very selective (>100-fold over hABHD6, >200-fold over hPLA2G7) inhibitor of monoacylglycerol lipase (MAGL) .1 Active in a rat formalin pain test at 3mg/kg. Orally bioavailable and CNS penetrant.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C
Available Sizes
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